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Existing medication could improve the health of people living with HIV

1+ hour, 53+ min ago  (473+ words) HIV exhausts the body's immune system by overactivating it, despite effective antiviral treatment. Existing medication could improve the health of people living with HIV HIV exhausts the body's immune system by overactivating it, despite effective antiviral treatment. Researchers from Link'ping…...

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Researchers explore "block and lock" strategy for functional HIV cure

14+ hour, 1+ min ago  (1097+ words) For millions of people living with HIV, a daily regimen of medications is a lifelong necessity. If they stop taking the drugs-commonly referred to as antiretroviral therapy-the virus usually rushes back within weeks. But not for everyone; scientists have been…...

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Protein targeted by cancer drugs may help the body fight influenza

5+ day, 3+ hour ago  (629+ words) A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX). Published in Cell Reports, the study found that Programmed Death-Ligand 1 (PD-L1), a protein best known for…...

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Children develop stronger immunity after repeated infections in nursery

5+ day, 3+ hour ago  (455+ words) Young children who attend nursery get sick more often than those who don't, but they will go on to have fewer illnesses during early school years, finds a new review of evidence by a group of parent-scientists involving University College…...

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Circular RNA produced by HIV boosts viral replication

1+ week, 2+ day ago  (641+ words) For decades scientists have recognized that human immunodeficiency virus (HIV) is a formidable viral pathogen. After years of probing work and extensive experimentation, a Yale research team has unlocked one of the reasons why that is. In a new study,…...

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Targeting two influenza proteins may reduce viral transmission

1+ week, 2+ day ago  (370+ words) A long-running debate in vaccine design revolves around whether a vaccine should be optimized to prevent the virus from replicating inside an infected host or prevent the virus from transmitting to others. New research led by Penn State scientists suggests…...

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Marburg virus enters human cells far more efficiently than Ebola

1+ week, 5+ day ago  (259+ words) In a new study published in Nature,University of Minnesota researchers found that the Marburg virus, one of the world's deadliest pathogens with an average 73% fatality rate, is unusually efficient at getting inside human cells. They also showed that the…...

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Most pandemic viruses show little adaptation before infecting humans

1+ week, 6+ day ago  (383+ words) Joel Wertheim, PhD, senior author and professor of medicine, Division of Infectious Diseases and Global Public Health, UC San Diego School of Medicine "From a broad epidemiological standpoint, our findings challenge the idea that pandemic viruses are evolutionarily special before…...

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New index provides state-level vulnerability to influenza-like illness

1+ week, 6+ day ago  (403+ words) Infectious disease can afflict a population in complex ways. Understanding the varying risks is an equally complex challenge. Their work, now published in the journal PLOS Computational Biology, provides a state-level vulnerability map revealing significant regional disparities between states at…...

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Researchers validate mpox antibody test during outbreak in Rwanda

1+ week, 6+ day ago  (368+ words) An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting. The test, an IgG ELISA assay, is…...