News
Asimov and AGC Biologics Agree to Develop New Viral Vector Production Approach
1+ hour, 52+ min ago (190+ words) Asimov and AGC Biologics Agree to Develop New Viral Vector Production Approach'Genetic Engineering and Biotechnology News CDMO AGC Biologics signed a licensing agreement for Asimov's off-the-shelf LV Edge Packaging cell line. AGC Biologics' Cell and Gene Center of Excellence in…...
Filovirus Detection by Immune System Improved by Nanoparticle Vaccine
3+ week, 4+ day ago (910+ words) New'vaccines that display'filovirus surface proteins on engineered, self-assembling protein nanoparticles'can improve immune system detection of the virus.'The nanoparticles triggered strong antibody responses across several filoviruses in mice, highlighting a promising path toward'viral protection.' The post Filovirus Detection by Immune…...
Viral sRNA Unlocks Phage Therapy Potential Against Drug-Resistant Bacteria
3+ week, 4+ day ago (340+ words) Plaques formed by phage lambda on an E. coli culture are being counted by Adi Levkowitz. [Yosef Adest] As the number of antibiotic-resistant infections continues to rise, scientists are looking to bacteriophages (phages), viruses that infect bacteria, as an approach to…...
Ebola and Marburg-Induced Gut Damage Modeled Using Organoids
1+ mon, 1+ day ago (357+ words) Colorized transmission electron microscopic image showing the filamentous and curved morphology of an Ebola virus particle. [CDC/ Frederick A. Murphy] Ebola virus and Marburg virus are both highly contagious filoviruses and are among the most lethal viruses known. Patient deaths are…...
Monkeypox Vaccine Breakthrough: AI Reveals New Target
1+ mon, 2+ day ago (316+ words) Structure of a surface protein on the monkeypox virus (MPXV OPG153, highlighted in pink) in complex with two neutralizing antibodies: 08E11 (highlighted in blue) and 12I12 (highlighted in yellow). [University of Texas at Austin] In 2022, monkeypox virus (mpox) caused more than 150,000 cases'causing flu-like…...
Viral Clearance Validation and Beyond: Building on Knowledge Gained from HIV
1+ mon, 1+ week ago (785+ words) Texcell has a long history and successful track record of ensuring safety from viral contamination (L to R) April Schubert, Jeff Schubert, and Tracy Schubert, opening their third viral clearance facility in the U.S. The latest, the state-of-the-art viral clearance facility in…...
HIV Integrase Captured by Cryo-EM in Two Structural States
1+ mon, 3+ week ago (544+ words) Symptoms from HIV infection can currently be managed with lifelong treatment. However, there is no cure and new targets are needed due to the development of drug resistance. A promising treatment target is the retroviral integrase enzyme which has two…...
Cell Line Ups Titer 7.5-fold for Adenovirus Production
1+ mon, 3+ week ago (251+ words) Researchers recently enhanced the titer of a cell line still in development to produce adenovirus viral vectors by 7.5-fold, and without the risk of also producing replication-competent adenoviruses (RCA). If approved by regulatory bodies, it will join a handful of…...
Cervical Cancer May Be Treatable with Intranasal Nanogel Vaccine
1+ mon, 4+ week ago (265+ words) The human papillomavirus (HPV) vaccine is a triumph of modern medicine'but it cannot eliminate an existing infection. Once HPV takes hold, no approved vaccines can stop its progression to cervical cancer, leaving surgery and chemotherapy as the main options. Researchers…...
Common Epstein–Barr Virus Reprograms B Cells to Drive Lupus
2+ mon, 13+ min ago (287+ words) Credit: Design Cells / iStock / Getty Images Plus About five million people worldwide have systemic lupus erythematosus (SLE), an autoimmune disease that damages organs and tissues throughout the body, including skin, joints, kidneys, heart, and nerves, with symptoms varying widely among…...