2+ day, 6+ hour ago   (290+ words) Jeffrey Hyams, MD, of the University of Connecticut and Connecticut Children’s Hospital in Hartford, Connecticut, shares results from the UNIFI JR trial evaluating ustekinumab in pediatric patients with ulcerative colitis who did not respond to conventional therapies. From these results…...

3+ day, 11+ hour ago   (141+ words) In a phase 2a study, the THR-β agonist ALG-055009, currently in clinical development, reduced liver fat in patients with metabolic dysfunction-associated steatohepatitis (MASH). The study authors also noted that of the 14 patients on stable GLP-1 receptor agonist therapy who were randomized…...

3+ week, 1+ day ago   (155+ words) I-STRONG, a novel intervention program for adolescent patients with sickle cell disease (SCD), offers an effective approach to chronic pain management based on a pilot study published in Blood Advances.1 Researchers at children’s hospitals in Atlanta and Cincinnati conducted a…...

3+ week, 2+ day ago   (283+ words) In patients with essential thrombocythemia (ET), the condition may feature calreticulin mutations that ET therapies can target. INCA033989, a novel monoclonal antibody in development for ET, operates in this manner, and a first-in-human phase 1 study evaluating this agent has yielded encouraging…...

3+ week, 3+ day ago   (187+ words) Random effects models were used to synthesize correlation coefficients, grouped odds ratios (ORs), and continuous ORs across studies. Of the 19 observational studies that were included, 10 contributed correlation coefficients, six provided grouped ORs, and three provided continuous ORs. The grouped OR…...

3+ week, 5+ day ago   (452+ words) DocWire News: For years, digital health efforts focused on expanding access to technology and connectivity. In your experience, why has access alone proven insufficient for improving patient outcomes? And at the same time, others have said that about 90% or nine…...

4+ week, 1+ day ago   (748+ words) Behind those decisions was a growing sense of fear. In conversations that used to focus on BP, diabetes, or medication management, physicians increasingly found themselves talking to patients about fear: fear of leaving home, fear of being separated from family…...

1+ mon, 15+ hour ago   (195+ words) Results from the analysis showed that healthcare spending grew by 1.8% every year from 2005 to 2023 for people in the top income quintile. It did not grow at all for people in the bottom quintile. This pattern fluctuated every now and then....

1+ mon, 6+ day ago   (694+ words) Docwire News Methotrexate Lab Monitoring Frequency: How Much Is Actually Necessary? Methotrexate (MTX) is considered the cornerstone of therapy for rheumatoid arthritis and is widely used to treat other systemic rheumatic diseases as well, including systemic lupus, psoriatic arthritis, and…...

1+ mon, 1+ week ago   (259+ words) Can AI Triage Help Match Patients to the Right Care Setting? The AI tool was launched through the health system’s website and its patient app, creating a digital entry point available around the clock. Patients could enter symptoms through a…...